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Type II Isopentenyl Diphosphate Isomerase: Probing the Mechanism with Alkyne/Allene Diphosphate Substrate Analogues

Isopentenyl diphosphate isomerase (IDI) catalyzes the interconversion of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), the basic five-carbon building blocks of isoprenoid molecules. Two structurally unrelated classes of IDI are known. Type I IPP isomerase (IDI-1) utilizes a di...

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Detalhes bibliográficos
Main Authors: Sharma, Nagendra K., Pan, Jian-Jung, Poulter, C. Dale
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912430/
https://ncbi.nlm.nih.gov/pubmed/20560533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100844e
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