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Isopentenyl Diphosphate Isomerase. Mechanism-Based Inhibition by Diene Analogues of Isopentenyl Diphosphate and Dimethylallyl Diphosphate

Isopentenyl diphosphate isomerase (IDI) catalyzes the interconversion of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). This is an essential step in the mevalonate entry into the isoprenoid biosynthetic pathway. The isomerization catalyzed by type I IDI involves protonation of...

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Sonraí Bibleagrafaíochta
Main Authors: Wu, Zheng, Wouters, Johan, Poulter, C. Dale
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2005
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2528281/
https://ncbi.nlm.nih.gov/pubmed/16332094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja056187h
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