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Isopentenyl Diphosphate Isomerase. Mechanism-Based Inhibition by Diene Analogues of Isopentenyl Diphosphate and Dimethylallyl Diphosphate

Isopentenyl diphosphate isomerase (IDI) catalyzes the interconversion of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). This is an essential step in the mevalonate entry into the isoprenoid biosynthetic pathway. The isomerization catalyzed by type I IDI involves protonation of...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Wu, Zheng, Wouters, Johan, Poulter, C. Dale
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2005
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2528281/
https://ncbi.nlm.nih.gov/pubmed/16332094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja056187h
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