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Isopentenyl Diphosphate Isomerase. Mechanism-Based Inhibition by Diene Analogues of Isopentenyl Diphosphate and Dimethylallyl Diphosphate

Isopentenyl diphosphate isomerase (IDI) catalyzes the interconversion of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). This is an essential step in the mevalonate entry into the isoprenoid biosynthetic pathway. The isomerization catalyzed by type I IDI involves protonation of...

詳細記述

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書誌詳細
主要な著者: Wu, Zheng, Wouters, Johan, Poulter, C. Dale
フォーマット: Artigo
言語:Inglês
出版事項: 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2528281/
https://ncbi.nlm.nih.gov/pubmed/16332094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja056187h
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