CERAMIDE CHANNELS: INFLUENCE OF MOLECULAR STRUCTURE ON CHANNEL FORMATION IN MEMBRANES

The sphingolipid, ceramide, self-assembles in the mitochondrial outer membrane (MOM), forming large channels capable of translocating proteins. These channels are believed to be involved in protein release from mitochondria, a key decision-making step. Synthetic analogs of ceramide, bearing modifica...

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Detalhes bibliográficos
Main Authors: Perera, Meenu N., Ganesan, Vidyaramanan, Siskind, Leah J., Szulc, Zdzislaw M., Bielawski, Jacek, Bielawska, Alicja, Bittman, Robert, Colombini, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319251/
https://ncbi.nlm.nih.gov/pubmed/22365970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2012.02.010
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