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Ceramide forms channels in mitochondrial outer membranes at physiologically relevant concentrations
Recent evidence suggests that the ability of ceramides to induce apoptosis is due to a direct action on mitochondria. Mitochondria are known to contain enzymes responsible for ceramide synthesis and hydrolysis and mitochondrial ceramide levels have been shown to be elevated prior to the mitochondria...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2246045/ https://ncbi.nlm.nih.gov/pubmed/16713754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2006.03.002 |
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