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Ceramide channel: structural basis for selective membrane targeting

A ceramide commonly found in mammalian cells, C(16)-ceramide (N-palmitoyl-D-erythrosphingosine), is capable of forming large, protein-permeable channels in the mitochondrial outer membrane (MOM). However, C(16)-ceramide is unable to permeabilize the plasma membrane of erythrocytes. This specificity...

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Bibliografiske detaljer
Udgivet i:Chem Phys Lipids
Main Authors: Perera, Meenu N., Ganesan, Vidyaramanan, Siskind, Leah J., Szulc, Zdzislaw M., Bielawska, Alicja, Bittman, Robert, Colombini, Marco
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718829/
https://ncbi.nlm.nih.gov/pubmed/26408265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chemphyslip.2015.09.007
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