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The Lipids C(2)- and C(16)-Ceramide Form Large Stable Channels: IMPLICATIONS FOR APOPTOSIS

We report that physiological concentrations of both short- and long-chain ceramides, despite being lipids, form large stable pores in membranes. Some of these pores should be large enough to allow cytochrome c to permeate. Dihydroceramide differs from ceramide by the reduction of one double bond, an...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Siskind, Leah J., Colombini, Marco
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2000
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2094390/
https://ncbi.nlm.nih.gov/pubmed/11027675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C000587200
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