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Ceramide Channels: Destabilization by Bcl-xL and Role in Apoptosis()
Ceramide is a bioactive sphingolipid involved in mitochondrial-mediated apoptosis. Our data suggest that ceramides directly regulate a key initiation step in apoptosis: mitochondrial outer membrane permeabilization (MOMP). MOMP allows release of intermembrane space proteins to the cytosol, inducing...
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| Publicado no: | Biochim Biophys Acta |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4554889/ https://ncbi.nlm.nih.gov/pubmed/26215742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2015.07.013 |
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