Distinct sites of action of Bcl-2 and Bcl-xL in the ceramide pathway of apoptosis.

We studied the inhibition of tumour necrosis factor alpha (TNFalpha)- and camptothecin-induced apoptosis by Bcl-2 and Bcl-xL as they relate to the ceramide pathway. Expression of either Bcl-2 or Bcl-xL provided significant protection from the apoptotic effects of TNFalpha or camptothecin. In contras...

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Bibliografske podrobnosti
Main Authors: El-Assaad, W, El-Sabban, M, Awaraji, C, Abboushi, N, Dbaibo, G S
Format: Artigo
Jezik:Inglês
Izdano: 1998
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1219927/
https://ncbi.nlm.nih.gov/pubmed/9841888
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