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Regulation of apoptosis by an intrinsically disordered region of Bcl-xL
Intrinsically disordered regions (IDRs) of proteins often regulate function upon posttranslational modifications (PTMs) through interactions with folded domains. An IDR linking two α-helices (α1–α2) of the anti-apoptotic protein, Bcl-xL, experiences several PTMs, which reduce anti-apoptotic activity...
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| Publicado en: | Nat Chem Biol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5899648/ https://ncbi.nlm.nih.gov/pubmed/29507390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-018-0011-x |
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