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Apoptosis and Oncogenesis: Give and Take in the BCL-2 Family

The mitochondrial pathway of apoptosis constitutes one of the main safeguards against tumorigenesis. The BCL-2 family includes the central players of this pathway that regulate cell fate though the control of mitochondrial outer membrane permeabilization (MOMP), and important progress has been made...

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Detalhes bibliográficos
Main Authors: Llambi, Fabien, Green, Douglas R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040981/
https://ncbi.nlm.nih.gov/pubmed/21236661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2010.12.001
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