A unified model of mammalian BCL-2 protein family interactions at the mitochondria

During apoptosis, the BCL-2 protein family controls Mitochondrial Outer Membrane Permeabilization (MOMP), but the dynamics of this regulation remains controversial. We employed chimeric proteins composed of exogenous BH3 domains inserted into a tBID backbone that can activate the pro-apoptotic effec...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Llambi, Fabien, Moldoveanu, Tudor, Tait, Stephen W.G., Bouchier-Hayes, Lisa, Temirov, Jamshid, McCormick, Laura L., Dillon, Christopher P., Green, Douglas R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221787/
https://ncbi.nlm.nih.gov/pubmed/22036586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.10.001
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados