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Anti-apoptotic Bcl-2 Family Proteins Disassemble Ceramide Channels
Early in mitochondria-mediated apoptosis, the mitochondrial outer membrane becomes permeable to proteins that, when released into the cytosol, initiate the execution phase of apoptosis. Proteins in the Bcl-2 family regulate this permeabilization, but the molecular composition of the mitochondrial ou...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2713582/ https://ncbi.nlm.nih.gov/pubmed/18171672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M706115200 |
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