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Ceramide Channels Increase the Permeability of the Mitochondrial Outer Membrane to Small Proteins

Ceramides are known to play a major regulatory role in apoptosis by inducing cytochrome c release from mitochondria. We have previously reported that C(2)- and C(16)-ceramide, but not dihydroceramide, form large channels in planar membranes (Siskind, L. J., and Colombini, M. (2001) J. Biol. Chem. 27...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Siskind, Leah J, Kolesnick, Richard N, Colombini, Marco
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2002
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2246046/
https://ncbi.nlm.nih.gov/pubmed/12006562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M200754200
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