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Ceramide Channels Increase the Permeability of the Mitochondrial Outer Membrane to Small Proteins
Ceramides are known to play a major regulatory role in apoptosis by inducing cytochrome c release from mitochondria. We have previously reported that C(2)- and C(16)-ceramide, but not dihydroceramide, form large channels in planar membranes (Siskind, L. J., and Colombini, M. (2001) J. Biol. Chem. 27...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2246046/ https://ncbi.nlm.nih.gov/pubmed/12006562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M200754200 |
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