A Semimechanistic Pharmacokinetic-Enzyme Turnover Model for Rifampin Autoinduction in Adult Tuberculosis Patients

The currently recommended doses of rifampin are believed to be at the lower end of the dose-response curve. Rifampin induces its own metabolism, although the effect of dose on the extent of autoinduction is not known. This study aimed to investigate rifampin autoinduction using a semimechanistic pha...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Smythe, Wynand, Khandelwal, Akash, Merle, Corinne, Rustomjee, Roxana, Gninafon, Martin, Bocar Lo, Mame, Sow, Oumou Bah, Olliaro, Piero L., Lienhardt, Christian, Horton, John, Smith, Peter, McIlleron, Helen, Simonsson, Ulrika S. H.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2012
Teme:
Pharmacology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318330/
https://ncbi.nlm.nih.gov/pubmed/22252827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05792-11
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items