Evidence for T Cell Help in the IgG Response against Tandemly Repetitive Trypanosoma cruzi B13 Protein in Chronic Chagas Disease Patients

The tandemly repetitive Trypanosoma cruzi B13 protein is an immunodominant antigen among Chagas disease patients. Such repetitive domains may behave as T-independent antigens. However, T cells can recognize B13 epitopes in an HLA class II-restricted fashion and could potentially provide cognate T ce...

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Bibliographische Detailangaben
Hauptverfasser: Duranti, Marcia, Camargo, Ludmila, Victora, Gabriel, Ianni, Barbara, Buck, Paula, Mady, Charles, Kalil, Jorge, Zingales, Bianca, Cunha-Neto, Edecio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2012
Schlagworte:
Clinical Study
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317355/
https://ncbi.nlm.nih.gov/pubmed/22523642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/635873
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