Evidence for T Cell Help in the IgG Response against Tandemly Repetitive Trypanosoma cruzi B13 Protein in Chronic Chagas Disease Patients

The tandemly repetitive Trypanosoma cruzi B13 protein is an immunodominant antigen among Chagas disease patients. Such repetitive domains may behave as T-independent antigens. However, T cells can recognize B13 epitopes in an HLA class II-restricted fashion and could potentially provide cognate T ce...

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Bibliografske podrobnosti
Main Authors: Duranti, Marcia, Camargo, Ludmila, Victora, Gabriel, Ianni, Barbara, Buck, Paula, Mady, Charles, Kalil, Jorge, Zingales, Bianca, Cunha-Neto, Edecio
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2012
Teme:
Clinical Study
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317355/
https://ncbi.nlm.nih.gov/pubmed/22523642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/635873
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