Evidence for T Cell Help in the IgG Response against Tandemly Repetitive Trypanosoma cruzi B13 Protein in Chronic Chagas Disease Patients

The tandemly repetitive Trypanosoma cruzi B13 protein is an immunodominant antigen among Chagas disease patients. Such repetitive domains may behave as T-independent antigens. However, T cells can recognize B13 epitopes in an HLA class II-restricted fashion and could potentially provide cognate T ce...

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Bibliografiske detaljer
Main Authors: Duranti, Marcia, Camargo, Ludmila, Victora, Gabriel, Ianni, Barbara, Buck, Paula, Mady, Charles, Kalil, Jorge, Zingales, Bianca, Cunha-Neto, Edecio
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2012
Fag:
Clinical Study
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317355/
https://ncbi.nlm.nih.gov/pubmed/22523642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/635873
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