Evidence for T Cell Help in the IgG Response against Tandemly Repetitive Trypanosoma cruzi B13 Protein in Chronic Chagas Disease Patients

The tandemly repetitive Trypanosoma cruzi B13 protein is an immunodominant antigen among Chagas disease patients. Such repetitive domains may behave as T-independent antigens. However, T cells can recognize B13 epitopes in an HLA class II-restricted fashion and could potentially provide cognate T ce...

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Main Authors: Duranti, Marcia, Camargo, Ludmila, Victora, Gabriel, Ianni, Barbara, Buck, Paula, Mady, Charles, Kalil, Jorge, Zingales, Bianca, Cunha-Neto, Edecio
Formáid: Artigo
Teanga:Inglês
Foilsithe: Hindawi Publishing Corporation 2012
Ábhair:
Clinical Study
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317355/
https://ncbi.nlm.nih.gov/pubmed/22523642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/635873
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