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Drug discovery for Chagas disease should consider Trypanosoma cruzi strain diversity
This opinion piece presents an approach to standardisation of an important aspect of Chagas disease drug discovery and development: selecting Trypanosoma cruzi strains for in vitro screening. We discuss the rationale for strain selection representing T. cruzi diversity and provide recommendations on...
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| Publié dans: | Mem Inst Oswaldo Cruz |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Instituto Oswaldo Cruz, Ministério da Saúde
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4238778/ https://ncbi.nlm.nih.gov/pubmed/25317712 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/0074-0276140156 |
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