Distamycins inhibit the binding of OTF-1 and NFE-1 transfactors to their conserved DNA elements.
We investigated the effects of the antiviral agent distamycin A and of a distamycin derivative (FCE 24517) which possesses antineoplastic activity on the binding of some regulatory proteins to DNA. Both compounds inhibited the binding to DNA of the ubiquitous octamer binding factor OTF 1 and of the...
Guardado en:
| Publicado en: | Nucleic Acids Res |
|---|---|
| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
1989
|
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC331721/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2922260/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/17.3.1051 |
| Etiquetas: |
Sin Etiquetas, Sea el primero en etiquetar este registro!
|