Distamycins inhibit the binding of OTF-1 and NFE-1 transfactors to their conserved DNA elements.

We investigated the effects of the antiviral agent distamycin A and of a distamycin derivative (FCE 24517) which possesses antineoplastic activity on the binding of some regulatory proteins to DNA. Both compounds inhibited the binding to DNA of the ubiquitous octamer binding factor OTF 1 and of the...

Celý popis

Podrobná bibliografie

Vydáno v:	Nucleic Acids Res
Hlavní autoři:	Broggini, M, Ponti, M, Ottolenghi, S, D'Incalci, M, Mongelli, N, Mantovani, R
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Oxford University Press 1989
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC331721/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2922260/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/17.3.1051
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!