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Proteasome Inhibitor Bortezomib Ameliorates Intestinal Injury in Mice
BACKGROUND: Bortezomib is a proteasome inhibitor that has shown impressive efficacy in the treatment of multiple myeloma. In mice, the addition of dextran sulfate sodium (DSS) to drinking water leads to acute colitis that can serve as an experimental animal model for human ulcerative colitis. METHOD...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3316702/ https://ncbi.nlm.nih.gov/pubmed/22479648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034587 |
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