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The resistance mechanisms of proteasome inhibitor bortezomib
The proteasome inhibitor, bortezomib, a boronic dipeptide which reversibly inhibit the chymotrypsin-like activity at the β5-subunit of proteasome (PSMB5), has marked efficacy against multiple myeloma and several non-Hodgkin’s lymphoma subtypes, and has a potential therapeutic role against other mali...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4177604/ https://ncbi.nlm.nih.gov/pubmed/24252210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2050-7771-1-13 |
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