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The resistance mechanisms of proteasome inhibitor bortezomib

The proteasome inhibitor, bortezomib, a boronic dipeptide which reversibly inhibit the chymotrypsin-like activity at the β5-subunit of proteasome (PSMB5), has marked efficacy against multiple myeloma and several non-Hodgkin’s lymphoma subtypes, and has a potential therapeutic role against other mali...

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Autors principals: Lü, Shuqing, Wang, Jianmin
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177604/
https://ncbi.nlm.nih.gov/pubmed/24252210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2050-7771-1-13
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