Alterations of the Intracellular Peptidome in Response to the Proteasome Inhibitor Bortezomib

Bortezomib is an antitumor drug that competitively inhibits proteasome beta-1 and beta-5 subunits. While the impact of bortezomib on protein stability is known, the effect of this drug on intracellular peptides has not been previously explored. A quantitative peptidomics technique was used to examin...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gelman, Julia S., Sironi, Juan, Berezniuk, Iryna, Dasgupta, Sayani, Castro, Leandro M., Gozzo, Fabio C., Ferro, Emer S., Fricker, Lloyd D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2013
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538785/
https://ncbi.nlm.nih.gov/pubmed/23308178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053263
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