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Peptidomic analysis of HEK293T cells: Effect of the proteasome inhibitor epoxomicin on intracellular peptides

Peptides derived from cytosolic, mitochondrial, and nuclear proteins have been detected in extracts of animal tissues and cell lines. To test whether the proteasome is involved in their formation, HEK293T cells were treated with epoxomicin (0.2 μM or 2 μM) for 1 hour and quantitative peptidomics ana...

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Detalhes bibliográficos
Main Authors: Fricker, Lloyd D., Gelman, Julia S., Castro, Leandro M., Gozzo, Fabio C., Ferro, Emer S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315381/
https://ncbi.nlm.nih.gov/pubmed/22304392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr2012076
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