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Proteasome Inhibitor Bortezomib Ameliorates Intestinal Injury in Mice

BACKGROUND: Bortezomib is a proteasome inhibitor that has shown impressive efficacy in the treatment of multiple myeloma. In mice, the addition of dextran sulfate sodium (DSS) to drinking water leads to acute colitis that can serve as an experimental animal model for human ulcerative colitis. METHOD...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yanaba, Koichi, Asano, Yoshihide, Tada, Yayoi, Sugaya, Makoto, Kadono, Takafumi, Sato, Shinichi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316702/
https://ncbi.nlm.nih.gov/pubmed/22479648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034587
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