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Deletion of the Cl(−)/HCO(3)(−) exchanger pendrin downregulates calcium-absorbing proteins in the kidney and causes calcium wasting
BACKGROUND. The epithelial calcium channel (ECaC) (TRPV5) and the Cl(−)/HCO(3)(−) exchanger pendrin (SLC26A4) are expressed on the apical membrane of tubular cells in the distal nephron and play essential roles in calcium re-absorption and bicarbonate secretion, respectively, in the kidney. METHODS....
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3315671/ https://ncbi.nlm.nih.gov/pubmed/21873623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfr505 |
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