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Accurate Prediction of Inducible Transcription Factor Binding Intensities In Vivo

DNA sequence and local chromatin landscape act jointly to determine transcription factor (TF) binding intensity profiles. To disentangle these influences, we developed an experimental approach, called protein/DNA binding followed by high-throughput sequencing (PB–seq), that allows the binding energy...

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Bibliografske podrobnosti
Main Authors: Guertin, Michael J., Martins, André L., Siepel, Adam, Lis, John T.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315474/
https://ncbi.nlm.nih.gov/pubmed/22479205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002610
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