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Accurate Prediction of Inducible Transcription Factor Binding Intensities In Vivo

DNA sequence and local chromatin landscape act jointly to determine transcription factor (TF) binding intensity profiles. To disentangle these influences, we developed an experimental approach, called protein/DNA binding followed by high-throughput sequencing (PB–seq), that allows the binding energy...

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Detalhes bibliográficos
Main Authors: Guertin, Michael J., Martins, André L., Siepel, Adam, Lis, John T.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315474/
https://ncbi.nlm.nih.gov/pubmed/22479205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002610
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