An NLRP7-Containing Inflammasome Mediates Recognition of Microbial Lipopeptides in Human Macrophages

Cytosolic pathogen- and damage-associated molecular patterns are sensed by pattern recognition receptors, including members of the nucleotide-binding domain and leucine-rich repeat containing gene family (NLR), which cause inflammasome assembly and caspase-1 activation to promote maturation and rele...

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Bibliografiske detaljer
Main Authors: Khare, Sonal, Dorfleutner, Andrea, Bryan, Nicole B., Yun, Chawon, Radian, Alexander D., de Almeida, Lucia, Rojanasakul, Yon, Stehlik, Christian
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315380/
https://ncbi.nlm.nih.gov/pubmed/22361007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.02.001
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