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NLRP7 and related inflammasome activating pattern recognition receptors and their function in host defense and disease

Host defense requires the maturation and release of the pro-inflammatory cytokines interleukin (IL)-1β and IL-18 and the induction of pyroptotic cell death, which depends on the activation of inflammatory Caspases within inflammasomes by innate immune cells. Several cytosolic Pattern recognition rec...

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Main Authors: Radian, Alexander D., de Almeida, Lucia, Dorfleutner, Andrea, Stehlik, Christian
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3722249/
https://ncbi.nlm.nih.gov/pubmed/23618810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micinf.2013.04.001
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