ATP binding by NLRP7 is required for inflammasome activation in response to bacterial lipopeptides

Nucleotide-binding oligimerization domain (NOD)-like receptors (NLRs) are pattern recognition receptors (PRRs) involved in innate immune responses. NLRs encode a central nucleotide-binding domain (NBD) consisting of the NAIP, CIITA, HET-E and TP1 (NACHT) domain and the NACHT associated domain (NAD),...

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Udgivet i:Mol Immunol
Main Authors: Radian, Alexander D., Khare, Sonal, Chu, Lan H., Dorfleutner, Andrea, Stehlik, Christian
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4565763/
https://ncbi.nlm.nih.gov/pubmed/26143398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2015.06.013
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