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A novel zinc-finger nuclease platform with a sequence-specific cleavage module
Zinc-finger nucleases (ZFNs) typically consist of three to four zinc fingers (ZFs) and the non-specific DNA-cleavage domain of the restriction endonuclease FokI. In this configuration, the ZFs constitute the binding module and the FokI domain the cleavage module. Whereas new binding modules, e.g. TA...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3315325/ https://ncbi.nlm.nih.gov/pubmed/22135304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1112 |
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