טוען...
An NF-κB pathway–mediated positive feedback loop amplifies Ras activity to pathological levels in mice
Genetic mutations that give rise to active mutant forms of Ras are oncogenic and found in several types of tumor. However, such mutations are not clear biomarkers for disease, since they are frequently detected in healthy individuals. Instead, it has become clear that elevated levels of Ras activity...
שמור ב:
| Main Authors: | , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Clinical Investigation
2012
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3314459/ https://ncbi.nlm.nih.gov/pubmed/22406536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI59743 |
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