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Intracellular Trypsin Induces Pancreatic Acinar Cell Death but Not NF-κB Activation
Premature intracellular activation of the digestive enzyme trypsinogen is considered to be the initiating event in pancreatitis. However, the direct consequences of intracellular trypsin activity have not previously been examined. In the current study, a mutant trypsinogen (paired basic amino acid c...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2719389/ https://ncbi.nlm.nih.gov/pubmed/19383608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.005520 |
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