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Intracellular activation of trypsinogen in transgenic mice induces acute but not chronic pancreatitis

BACKGROUND AND AIMS: Premature intra-acinar activation of trypsinogen is widely considered key for both the initiation of acute pancreatitis and the development of chronic pancreatitis. However, the biological consequences of intracellular trypsinogen activation have not been directly examined. To d...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Gut
Hauptverfasser: Gaiser, Sebastian, Daniluk, Jaroslaw, Liu, Yan, Tsou, Lilian, Chu, Jun, Lee, Woojin, Longnecker, Daniel S, Logsdon, Craig D, Ji, Baoan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4304390/
https://ncbi.nlm.nih.gov/pubmed/21471572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2010.226175
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