Ras Activity Levels Control the Development of Pancreatic Diseases

BACKGROUND & AIMS: Differentiated pancreatic acinar cells expressing endogenous levels of mutant K-Ras do not spontaneously develop pancreatic ductal adenocarcinoma (PDAC). However, we hypothesized that acinar cells would develop PDAC in the presence of Ras activity levels mimicking those of hum...

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Detalhes bibliográficos
Main Authors: Ji, Baoan, Tsou, Lilian, Wang, Huamin, Gaiser, Sebastian, Chang, David Z., Daniluk, Jaroslaw, Bi, Yan, Grote, Tobias, Longnecker, Daniel S., Logsdon, Craig D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789008/
https://ncbi.nlm.nih.gov/pubmed/19501586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2009.05.052
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