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Ras Activity Levels Control the Development of Pancreatic Diseases
BACKGROUND & AIMS: Differentiated pancreatic acinar cells expressing endogenous levels of mutant K-Ras do not spontaneously develop pancreatic ductal adenocarcinoma (PDAC). However, we hypothesized that acinar cells would develop PDAC in the presence of Ras activity levels mimicking those of hum...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2789008/ https://ncbi.nlm.nih.gov/pubmed/19501586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2009.05.052 |
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