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Transgenic Expression of PRSS1(R122H) Sensitizes Mice to Pancreatitis
BACKGROUND & AIMS: Mutations in the trypsinogen gene (PRSS1) cause human hereditary pancreatitis. However, it is not clear how mutant forms of PRSS1 contribute to disease development. We studied the effects of expressing mutant forms of human PRSS1 in mice. METHODS: We expressed forms of PRSS1 w...
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| Publicado no: | Gastroenterology |
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| Principais autores: | , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7580257/ https://ncbi.nlm.nih.gov/pubmed/31419436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2019.08.016 |
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