Transgenic Expression of PRSS1(R122H) Sensitizes Mice to Pancreatitis

BACKGROUND & AIMS: Mutations in the trypsinogen gene (PRSS1) cause human hereditary pancreatitis. However, it is not clear how mutant forms of PRSS1 contribute to disease development. We studied the effects of expressing mutant forms of human PRSS1 in mice. METHODS: We expressed forms of PRSS1 w...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Gastroenterology
Glavni autori: Huang, Haojie, Swidnicka-Siergiejko, Agnieszka Katarzyna, Daniluk, Jaroslaw, Gaiser, Sebastian, Yao, Yao, Peng, Lisi, Zhang, Yang, Liu, Yan, Dong, Minyu, Zhan, Xianbao, Wang, Huamin, Bi, Yan, Li, Zhaoshen, Ji, Baoan, Logsdon, Craig D.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7580257/
https://ncbi.nlm.nih.gov/pubmed/31419436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2019.08.016
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items