Transgenic expression of cyclooxygenase-2 in pancreatic acinar cells induces chronic pancreatitis

Replacement of the exocrine parenchyma by fibrous tissue is a main characteristic of chronic pancreatitis. Understanding the mechanisms of pancreatic fibrogenesis is critical for the development of preventive and therapeutic interventions. Cyclooxygenase-2 (COX-2), a rate-limiting enzyme for prostag...

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Vydáno v:Am J Physiol Gastrointest Liver Physiol
Hlavní autoři: Huang, Haojie, Chen, Jiaxiang, Peng, Lisi, Yao, Yao, Deng, Defeng, Zhang, Yang, Liu, Yan, Wang, Huamin, Li, Zhaoshen, Bi, Yan, Haddock, Ashley N., Zhan, Xianbao, Lu, Weiqin, Logsdon, Craig D., Ji, Baoan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6383372/
https://ncbi.nlm.nih.gov/pubmed/30431318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00096.2018
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