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Identification of exosite residues of factor Xa involved in recognition of PAR-2 on endothelial cells

Recent results have indicated that factor Xa (FXa) cleaves protease-activated receptor 2 (PAR-2) to elicit protective intracellular signaling responses in endothelial cells. In this study, we investigated the molecular determinants of the specificity of FXa interaction with PAR-2 by monitoring the c...

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Bibliografiska uppgifter
Huvudupphovsmän: Manithody, Chandrashekhara, Yang, Likui, Rezaie, Alireza R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314109/
https://ncbi.nlm.nih.gov/pubmed/22409427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300200p
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