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Identification of a Basic Region on Tissue Factor that Interacts with the First Epidermal Growth Factor-like Domain of Factor X

Tissue factor (TF) facilitates the recognition and rapid activation of factor X (fX) by factor VIIa (fVIIa) in the extrinsic Xase pathway. TF makes extensive interactions with both light and heavy chains of fVIIa, however, with the exception of a basic recognition site for the Gla-domain of fX, no o...

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Autors principals: Manithody, Chandrashekhara, Yang, Likui, Rezaie, Alireza R.
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518643/
https://ncbi.nlm.nih.gov/pubmed/17323935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi6025193
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