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Association between bilirubin and cardiovascular disease risk factors: using Mendelian randomization to assess causal inference

BACKGROUND: Elevated serum bilirubin has been associated with reduced risk of cardiovascular disease (CVD). However, serum bilirubin is also related with several potential confounders related to CVD, such as obesity. Mendelian randomization has been proposed as a method to address challenges to vali...

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Hlavní autoři: McArdle, Patrick F, Whitcomb, Brian W, Tanner, Keith, Mitchell, Braxton D, Shuldiner, Alan R, Parsa, Afshin
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3313889/
https://ncbi.nlm.nih.gov/pubmed/22416852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2261-12-16
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