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Association between bilirubin and cardiovascular disease risk factors: using Mendelian randomization to assess causal inference

BACKGROUND: Elevated serum bilirubin has been associated with reduced risk of cardiovascular disease (CVD). However, serum bilirubin is also related with several potential confounders related to CVD, such as obesity. Mendelian randomization has been proposed as a method to address challenges to vali...

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Detalhes bibliográficos
Main Authors: McArdle, Patrick F, Whitcomb, Brian W, Tanner, Keith, Mitchell, Braxton D, Shuldiner, Alan R, Parsa, Afshin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3313889/
https://ncbi.nlm.nih.gov/pubmed/22416852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2261-12-16
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