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Association between bilirubin and cardiovascular disease risk factors: using Mendelian randomization to assess causal inference

BACKGROUND: Elevated serum bilirubin has been associated with reduced risk of cardiovascular disease (CVD). However, serum bilirubin is also related with several potential confounders related to CVD, such as obesity. Mendelian randomization has been proposed as a method to address challenges to vali...

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Autors principals: McArdle, Patrick F, Whitcomb, Brian W, Tanner, Keith, Mitchell, Braxton D, Shuldiner, Alan R, Parsa, Afshin
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3313889/
https://ncbi.nlm.nih.gov/pubmed/22416852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2261-12-16
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