Imipramine blocks ethanol-induced ASMase activation, ceramide generation, and PP2A activation, and ameliorates hepatic steatosis in ethanol-fed mice

Our previous data showed the inhibitory effect of ethanol on AMP-activated protein kinase phosphorylation, which appears to be mediated, in part, through increased levels of hepatic ceramide and activation of protein phosphatase 2A (Liangpunsakul S, Sozio MS, Shin E, Zhao Z, Xu Y, Ross RA, Zeng Y, C...

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Detaylı Bibliyografya
Asıl Yazarlar: Liangpunsakul, Suthat, Rahmini, Yasmeen, Ross, Ruth A., Zhao, Zhenwen, Xu, Yan, Crabb, David W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2012
Konular:
Liver and Biliary Tract
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311438/
https://ncbi.nlm.nih.gov/pubmed/22194417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00455.2011
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