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Fine epitope mapping within the pathogenic thyroglobulin peptide 2340–2359: minimal epitopes retaining antigenicity across various MHC haplotypes are not necessarily immunogenic

We have previously reported that the 20-mer peptide p2340 (amino acids 2340–2359), of human thyroglobulin (Tg) has the unique feature that it causes experimental autoimmune thyroiditis (EAT) in mouse strains bearing high-responder (HR) or low-responder (LR) MHC haplotypes in Tg-induced EAT. In this...

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Detalhes bibliográficos
Main Authors: Hatzioannou, Aikaterini, Alevizaki, Maria, Carayanniotis, George, Lymberi, Peggy
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311047/
https://ncbi.nlm.nih.gov/pubmed/22098450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2011.03538.x
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