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Evidence for intramolecular B-cell epitope spreading during experimental immunization with an immunogenic thyroglobulin peptide

Thyroglobulin (Tg) is a target autoantigen in autoimmune thyroid diseases, such as Graves’ disease (GD) and Hashimoto's thyroiditis. In a previous study we identified three 20mer Tg peptides bearing epitopes of autoantibodies associated with GD (TgP15, TgP26 and TgP41: sequences 2339–2358, 2471...

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Detalhes bibliográficos
Main Authors: THRASYVOULIDES, A, LYMBERI, P
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1808729/
https://ncbi.nlm.nih.gov/pubmed/12780685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2003.02162.x
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