Thyroxine-Binding Antibodies Inhibit T Cell Recognition of a Pathogenic Thyroglobulin Epitope

Thyroid hormone-binding (THB) Abs are frequently detected in autoimmune thyroid disorders but it is unknown whether they can exert immunoregulatory effects. We report that a THB mAb recognizing the 5′ iodine atom of the outer phenolic ring of thyroxine (T4) can block T cell recognition of the pathog...

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Hlavní autoři: Dai, Yang D., Eliades, Petros, Carayanniotis, Karen A., McCormick, Daniel J., Kong, Yi-chi M., Magafa, Vassiliki, Cordopatis, Paul, Lymberi, Peggy, Carayanniotis, George
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583135/
https://ncbi.nlm.nih.gov/pubmed/15728526
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