A Novel H2A(−)E(+) Transgenic Model Susceptible to Human but not Mouse Thyroglobulin-Induced Autoimmune Thyroiditis: Identification of Mouse Pathogenic Epitopes

The A(−)E(+) transgenic mouse is highly susceptible to human thyroglobulin (hTg)-induced thyroiditis, but strongly tolerant to a challenge by mouse thyroglobulin (mTg), in stark contrast to traditionally susceptible strains, wherein mTg induces stronger thyroiditis. To identify mouse thyroid epitope...

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Hlavní autoři: Brown, Nicholas K., McCormick, Daniel J., Brusic, Vladimir, David, Chella S., Kong, Yi-chi M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2483956/
https://ncbi.nlm.nih.gov/pubmed/18489063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2008.02.002
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